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Legal obligation in the general population: face mask influence on endophthalmitis after intravitreal injection.
Neubauer, Jonas; Gklavas, Konstantinos; Kortüm, Friederike; Gosheva, Mariya; Bartz-Schmidt, Karl Ulrich; Ziemssen, Focke.
  • Neubauer J; Center for Ophthalmology, University Hospital Tuebingen, Elfriede-Aulhorn-Str. 7, 72076, Tuebingen, Germany. StudyJN@outlook.com.
  • Gklavas K; Center for Ophthalmology, University Hospital Tuebingen, Elfriede-Aulhorn-Str. 7, 72076, Tuebingen, Germany.
  • Kortüm F; Center for Ophthalmology, University Hospital Tuebingen, Elfriede-Aulhorn-Str. 7, 72076, Tuebingen, Germany.
  • Gosheva M; Center for Ophthalmology, University Hospital Tuebingen, Elfriede-Aulhorn-Str. 7, 72076, Tuebingen, Germany.
  • Bartz-Schmidt KU; Center for Ophthalmology, University Hospital Tuebingen, Elfriede-Aulhorn-Str. 7, 72076, Tuebingen, Germany.
  • Ziemssen F; Center for Ophthalmology, University Hospital Tuebingen, Elfriede-Aulhorn-Str. 7, 72076, Tuebingen, Germany.
Graefes Arch Clin Exp Ophthalmol ; 2022 Aug 06.
Article in English | MEDLINE | ID: covidwho-2243725
ABSTRACT

PURPOSE:

To investigate whether compulsory face masking in public life changes the incidence or pattern of post-injection endophthalmitis (PIE). PATIENTS AND

METHODS:

All injections of bevacizumab, ranibizumab, aflibercept, dexamethasone or triamcinolone between 01/01/2015 and 12/31/2021 at the University Eye Clinic of Tuebingen were included in this retrospective analysis. The injection procedure itself was unchanged since 2015 and included the use of a sterile drape covering the head up to the shoulders which prevents airflow toward the eye. Furthermore, all staff wore a face mask and gloves at all times. The two study periods were defined by the introduction of a compulsory face masking rule in public life (01/01/2015 until 04/27/2020 vs. 04/28/2020 until 12/31/2021).

RESULTS:

A total of 83,543 injections were performed in the tertiary eye clinic, associated with a total of 20 PIE (0.024%, 1/4177 injections). Of these, thirteen PIE were documented during the pre-pandemic period (0.021%, 1/4773 injections) and seven PIE during the pandemic period (0.033%, 1/3071 injections). No significant difference in PIE risk was observed (p = 0.49), and there was no case of oral flora associated PIE.

CONCLUSION:

Although some potential confounders (wearing time, skin flora) could not be considered, there was no clear signal that the introduction of compulsory face masking in public life did alter the risk for PIE in our patient population. Three and six months after PIE, no difference in visual acuity was detectable between the two study periods.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Language: English Year: 2022 Document Type: Article Affiliation country: S00417-022-05768-6

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Language: English Year: 2022 Document Type: Article Affiliation country: S00417-022-05768-6