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Parkinsonism associated with viral infection.
Ivan, Irina; Irincu, Laura; Diaconu, Stefania; Falup-Pecurariu, Cristian.
  • Ivan I; County Clinic Hospital, Brașov, Romania.
  • Irincu L; County Clinic Hospital, Brașov, Romania.
  • Diaconu S; County Clinic Hospital, Brașov, Romania; Faculty of Medicine, Transilvania University, Brașov, Romania. Electronic address: stefi_diaconu@yahoo.com.
  • Falup-Pecurariu C; County Clinic Hospital, Brașov, Romania; Faculty of Medicine, Transilvania University, Brașov, Romania.
Int Rev Neurobiol ; 165: 1-16, 2022.
Article in English | MEDLINE | ID: covidwho-1982432
ABSTRACT
There are several known causes of secondary parkinsonism, the most common being head trauma, stroke, medications, or infections. A growing body of evidence suggests that viral agents may trigger parkinsonian symptoms, but the exact pathological mechanisms are still unknown. In some cases, lesions or inflammatory processes in the basal ganglia or substantia nigra have been found to cause reversible or permanent impairment of the dopaminergic pathway, leading to the occurrence of extrapyramidal symptoms. This chapter reviews current data regarding the viral agents commonly associated with parkinsonism, such as Epstein Barr virus (EBV), hepatitis viruses, human immunodeficiency virus (HIV), herpes viruses, influenza virus, coxsackie virus, and Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). We present possible risk factors, proposed pathophysiology mechanisms, published case reports, common associations, and prognosis in order to offer a concise overview of the viral spectrum involved in parkinsonism.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Virus Diseases / Epstein-Barr Virus Infections / Parkinsonian Disorders / COVID-19 Type of study: Diagnostic study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Int Rev Neurobiol Year: 2022 Document Type: Article Affiliation country: Bs.irn.2022.07.005

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Virus Diseases / Epstein-Barr Virus Infections / Parkinsonian Disorders / COVID-19 Type of study: Diagnostic study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Int Rev Neurobiol Year: 2022 Document Type: Article Affiliation country: Bs.irn.2022.07.005