Your browser doesn't support javascript.
Derivation and validation of sex-specific continuous metabolic syndrome scores for the Mexican adult population.
Pérez-Castro, Eduardo; Godínez-Jaimes, Flaviano; Vázquez-Medina, Martín Uriel; Ocharan-Hernández, María Esther; Vargas-De-León, Cruz.
  • Pérez-Castro E; Maestría en Matemáticas Aplicadas, Facultad de Matemáticas, Universidad Autónoma de Guerrero, Chilpancingo, Guerrero, Mexico.
  • Godínez-Jaimes F; Maestría en Matemáticas Aplicadas, Facultad de Matemáticas, Universidad Autónoma de Guerrero, Chilpancingo, Guerrero, Mexico.
  • Vázquez-Medina MU; Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City, Mexico.
  • Ocharan-Hernández ME; Departamento de Investigación, Hospital Central Militar, Secretaria de la Defensa Nacional, Mexico City, Mexico.
  • Vargas-De-León C; Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City, Mexico.
Sci Rep ; 12(1): 9659, 2022 06 10.
Article in English | MEDLINE | ID: covidwho-1984407
ABSTRACT
Traditionally the diagnosis of Metabolic syndrome (MetS) is binary (present/absent). The goal of this work is to propose a sex-specific continuous score to measure the severity of MetS in Mexican adults using waist circumference and body mass index as adiposity measures. MetSx-WC and MetSx-BMI indexes by sex were derived by confirmatory factor analysis (CFA) using data for 6567 adult participants of the National Health and Nutrition Survey 2018. The overall fit of the two proposed CFA models was excellent. We then validated these scores using a community-based health study of 862 university participants and determined that the reliability and strength of agreement between the MetSx-WC and MetSx-BMI scores were excellent. The ROC analysis of the resulting indexes indicates that they have excellent ability to discriminate a MetS classification according to the different criteria. The correlations of MetSx scores and surrogate markers of insulin resistance and obesity ranged from weak to strong. Subsequently, a retrospective study of 310 hospitalized patients with COVID-19 was used to determined that MetSx-BMI score was associated with the mortality of patients with COVID-19. The proposed indices provide a continuous measure in the identification of MetS risk in Mexican adults.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Metabolic Syndrome / COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Adult / Female / Humans / Male Country/Region as subject: Mexico Language: English Journal: Sci Rep Year: 2022 Document Type: Article Affiliation country: S41598-022-10963-w

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Metabolic Syndrome / COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Adult / Female / Humans / Male Country/Region as subject: Mexico Language: English Journal: Sci Rep Year: 2022 Document Type: Article Affiliation country: S41598-022-10963-w