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Sensitivity of the Elecsys Nucleocapsid Assay for the Detection of Preceding SARS-CoV-2 Infections.
Grunau, Brian; Tom, Janessa; Asamoah-Boaheng, Michael; O'Brien, Sheila F; Drews, Steven J; Sediqi, Sadaf; Lavoie, Pascal M; Barakauskas, Vilte; Goldfarb, David M.
  • Grunau B; Centre for Health Evaluation & Outcome Sciences, St. Paul's Hospital, Vancouver, British Columbia, Canada.
  • Tom J; British Columbia Emergency Health Services, Vancouver, British Columbia, Canada.
  • Asamoah-Boaheng M; Department of Emergency Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • O'Brien SF; Canadian Blood Services, Ottawa, Ontario, Canada.
  • Drews SJ; Canadian Blood Services, Ottawa, Ontario, Canada.
  • Sediqi S; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Lavoie PM; Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
  • Barakauskas V; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Goldfarb DM; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Open Forum Infect Dis ; 9(8): ofac349, 2022 Aug.
Article in English | MEDLINE | ID: covidwho-1985109
ABSTRACT
Nucleocapsid serological assay sensitivity to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections among vaccinees and for Omicron cases is unclear. In this prospective study, the Elecsys nucleocapsid assay was 89% sensitive in identifying SARS-CoV-2 infections 14-607 days pre-blood collection. Sensitivity was similar when comparing by vaccination status, and in Omicron (vs pre-Omicron) cases.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study Topics: Vaccines / Variants Language: English Journal: Open Forum Infect Dis Year: 2022 Document Type: Article Affiliation country: Ofid

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study Topics: Vaccines / Variants Language: English Journal: Open Forum Infect Dis Year: 2022 Document Type: Article Affiliation country: Ofid