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Changing Epidemiology of Acute Viral Respiratory Infections in Hospitalized Children: The Post-Lockdown Effect.
Maglione, Marco; Pascarella, Antonia; Botti, Chiara; Ricci, Giuseppe; Morelli, Fiorella; Camelia, Fabiana; Micillo, Alberto; Calì, Camilla; Savoia, Fabio; Tipo, Vincenzo; Giannattasio, Antonietta.
  • Maglione M; Pediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
  • Pascarella A; Pediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
  • Botti C; Laboratory of Clinical Pathology, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
  • Ricci G; Laboratory of Clinical Pathology, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
  • Morelli F; Laboratory of Clinical Pathology, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
  • Camelia F; Laboratory of Clinical Pathology, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
  • Micillo A; Laboratory of Clinical Pathology, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
  • Calì C; Childhood Cancer Registry of Campania, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
  • Savoia F; Childhood Cancer Registry of Campania, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
  • Tipo V; Pediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
  • Giannattasio A; Pediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
Children (Basel) ; 9(8)2022 Aug 17.
Article in English | MEDLINE | ID: covidwho-1987677
ABSTRACT
Several reports highlighted how public health measures aimed at limiting severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) circulation have likely contributed to reducing the circulation of other respiratory viruses, particularly during the first year of the COVID-19 pandemic. We evaluated the epidemiology of acute respiratory infections in a large cohort of hospitalized children during the third year of the pandemic (2021-2022). We retrospectively analyzed data from the health records of children (<14 years) hospitalized for acute respiratory infections between 1 July 2021 and 31 March 2022. A total of 1763 respiratory panels were collected. Overall, 1269 (72%) panels hadpositive results for at least one pathogen. Most positive panels (53.8%) belonged to patients aged 1-12 months. The most detected pathogen was respiratory syncytial virus (RSV) (57.8% of positive panels). The RSV peak occurred in November 2021. Nine hundred and forty-five (74.5%) panels were positive for one pathogen while three hundred and twenty-four (25.5%) showed multiple infections. Patients with multiple infections were significantly older than those with a single infection. The 2021-2022 peak of RSV infection in Italy occurred earlier than in the previous pre-pandemic seasons. A high number of children have been hospitalized because of acute viral infections also due to less aggressive viruses.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Language: English Year: 2022 Document Type: Article Affiliation country: Children9081242

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Language: English Year: 2022 Document Type: Article Affiliation country: Children9081242