[Proteomic saliva assay in patients with COVID-19]. / Proteomnyi analiz slyuny u patsientov s COVID-19.
Stomatologiia (Mosk)
; 101(4): 34-37, 2022.
Article
in Russian
| MEDLINE | ID: covidwho-1988653
ABSTRACT
THE AIM OF THE STUDY Was to perform proteomic saliva assay in order to reveal mechanisms of the oral pathology caused by COVID-19. MATERIALS AND METHODS:
Proteomic analysis was performed to compare saliva proteins profile in healthy individuals (10 samples) and patients with COVID-19 (30 samples).RESULTS:
The obtained results of the saliva samples study in patients with COVID-19 indicate activation in the oral tissues the pathways of the cell renewal, apoptosis, DNA exchange processes and chromatin remodelling; there are also marked signs of immune response reactivation and immunostimulation.CONCLUSION:
Of all the proteins presented, the saliva of patients with COVID-19 33 proteins have an intersection with GO-annotated proteins of inflammation and epithelial cornification.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Proteomics
/
COVID-19
Limits:
Humans
Language:
Russian
Journal:
Stomatologiia (Mosk)
Year:
2022
Document Type:
Article
Affiliation country:
Stomat202210104134
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