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Effects of the COVID-19 pandemic on acute coronary syndromes in Germany during the first wave: the COVID-19 collateral damage study.
Zeymer, Uwe; Ahmadli, Vusal; Schneider, Steffen; Werdan, Karl; Weber, Michael; Hohenstein, Sven; Hindricks, Gerhard; Desch, Steffen; Bollmann, Andreas; Thiele, Holger.
  • Zeymer U; Medizinische Klinik B, Klinikum Ludwigshafen, Klinik für Innere Medizin/Kardiologie, Bremserstr. 79, 67063, Ludwigshafen, Germany. uwe.zeymer@t-online.de.
  • Ahmadli V; Institut für Herzinfarktforschung, Ludwigshafen, Germany. uwe.zeymer@t-online.de.
  • Schneider S; DGK Zentrum für Kardiologische Versorgungsforschung, Düsseldorf, Germany. uwe.zeymer@t-online.de.
  • Werdan K; Department of Cardiology, Heart Center Leipzig at University of Leipzig, Strümpellstraße 39, 04289, Leipzig, Germany.
  • Weber M; Leipzig Heart Institute, Leipzig, Germany.
  • Hohenstein S; Institut für Herzinfarktforschung, Ludwigshafen, Germany.
  • Hindricks G; DGK Zentrum für Kardiologische Versorgungsforschung, Düsseldorf, Germany.
  • Desch S; DGK Zentrum für Kardiologische Versorgungsforschung, Düsseldorf, Germany.
  • Bollmann A; Universität Halle, Halle, Germany.
  • Thiele H; Verband der Leitenden Krankenhausärzte Deutschlands e.V., Karlsruhe, Germany.
Clin Res Cardiol ; 2022 Aug 17.
Article in English | MEDLINE | ID: covidwho-2288440
ABSTRACT

BACKGROUND:

Reports about the influence of the COVID-19 pandemic on the number of hospital admissions and in-hospital mortality during the first wave between March and May 2020 showed conflicting results and are limited by single-center or limited regional multicenter datasets. Aim of this analysis covering all German federal states was the comprehensive description of hospital admissions and in-hospital mortality during the first wave of the COVID-19 pandemic. METHODS AND

RESULTS:

We conducted an observational study on hospital routine data (§21 KHEntgG) and included patients with the main diagnosis of acute myocardial infarction (ICD 21 and ICD 22). A total of 159 hospitals included 36,329 patients in the database, with 12,497 patients admitted with ST-elevation myocardial infarction (STEMI) and 23,832 admitted with non-ST-elevation myocardial infarction (NSTEMI). There was a significant reduction in the number of patients admitted with STEMI (3748 in 2020, 4263 in 2019 and 4486 in 2018; p < 0.01) and NSTEMI (6957 in 2020, 8437 in 2019 and 8438 in 2020; p < 0.01). These reductions were different between the Federal states of Germany. Percutaneous coronary intervention was performed more often in 2020 than in 2019 (odds ratio 1.13, 95% confidence interval [CI] 1.06-1.21) and 2018 (odds ratio 1.20, 95% CI 1.12-1.29) in NSTEMI and more often than in 2018 (odds ratio 1.26, 95% CI 1.10-1.43) in STEMI. The in-hospital mortality did not differ between the years for STEMI and NSTEMI, respectively.

CONCLUSIONS:

In this large representative sample size of hospitals in Germany, we observed significantly fewer admissions for NSTEMI and STEMI during the first COVID-19 wave, while quality of in-hospital care and in-hospital mortality were not affected. Admissions for STEMI and NSTEMI during the months March to May over 3 years and corresponding in-hospital mortality for patients with STEMI and NSTEMI in 159 German hospitals. (p-value for admissions 2020 versus 2019 and 2018 < 0.01; p-value for mortality n.s.).
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study Language: English Journal subject: Cardiology Year: 2022 Document Type: Article Affiliation country: S00392-022-02082-3

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study Language: English Journal subject: Cardiology Year: 2022 Document Type: Article Affiliation country: S00392-022-02082-3