Changes in preterm birth during the COVID-19 pandemic by duration of exposure and race and ethnicity.
J Perinatol
; 42(10): 1346-1352, 2022 10.
Article
in English
| MEDLINE | ID: covidwho-1991551
ABSTRACT
OBJECTIVE:
We aimed to determine whether coronavirus-disease-2019 (COVID-19) pandemic exposure duration was associated with PTB and if the pandemic modified racial disparities. STUDYDESIGN:
We analyzed Philadelphia births and replicated in New Haven. Compared to matched months in two prior years, we analyzed overall PTB, specific PTB phenotypes, and stillbirth.RESULTS:
Overall, PTB was similar between periods with the following exceptions. Compared to pre-pandemic, early pregnancy (<14 weeks') pandemic exposure was associated with lower risk of PTB < 28 weeks' (aRR 0.60 [0.30-1.10]) and later exposure with higher risk (aRR 1.77 [0.78-3.97]) (interaction p = 0.04). PTB < 32 weeks' among White patients decreased during the pandemic, resulting in non-significant widening of the Black-White disparity from aRR 2.51 (95%CI 1.53-4.16) to aRR 4.07 (95%CI 1.56-12.01) (interaction P = 0.41). No findings replicated in New Haven.CONCLUSION:
We detected no overall pandemic effects on PTB, but potential indirect benefits for some patients which could widen disparities remains possible.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Premature Birth
/
COVID-19
Type of study:
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Female
/
Humans
/
Infant, Newborn
/
Pregnancy
Language:
English
Journal:
J Perinatol
Journal subject:
Perinatology
Year:
2022
Document Type:
Article
Affiliation country:
S41372-022-01488-1
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