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Long-term spill-over impact of COVID-19 on health and healthcare of people with non-communicable diseases: a study protocol for a population-based cohort and health economic study.
Youn, Hin Moi; Quan, Jianchao; Mak, Ivy Lynn; Yu, Esther Yee Tak; Lau, Chak Sing; Ip, Mary Sau Man; Tang, Sydney Chi Wai; Wong, Ian Chi Kei; Lau, Kui Kai; Lee, Michael Shing Fung; Ng, Carmen S; Grépin, Karen Ann; Chao, David Vai Kiong; Ko, Welchie Wai Kit; Lam, Cindy Lo Kuen; Wan, Eric Yuk Fai.
  • Youn HM; Department of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Quan J; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Mak IL; Department of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Yu EYT; Department of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Lau CS; School of Clinical Medicine, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Ip MSM; Division of Respiratory, Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Tang SCW; Division of Nephrology, Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Wong ICK; Centre for Safe Medication Practice and research, Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR, China.
  • Lau KK; School of Pharmacy, University College London, London, UK.
  • Lee MSF; Aston Pharmacy School, Aston University, Birmingham, UK.
  • Ng CS; Department of Pharmacy, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
  • Grépin KA; Laboratory of Data Discovery for Health (D24H), Hong Kong SAR, China.
  • Chao DVK; Division of Neurology, Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
  • Ko WWK; The State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong SAR, China.
  • Lam CLK; Department of Clinical Oncology, Tuen Mun Hospital, Hospital Authority, Hong Kong SAR, China.
  • Wan EYF; Department of Clinical Oncology, Queen Mary Hospital, Hong Kong SAR, China.
BMJ Open ; 12(8): e063150, 2022 08 16.
Article in English | MEDLINE | ID: covidwho-1993028
ABSTRACT

INTRODUCTION:

The COVID-19 pandemic has a significant spill-over effect on people with non-communicable diseases (NCDs) over the long term, beyond the direct effect of COVID-19 infection. Evaluating changes in health outcomes, health service use and costs can provide evidence to optimise care for people with NCDs during and after the pandemic, and to better prepare outbreak responses in the future. METHODS AND

ANALYSIS:

This is a population-based cohort study using electronic health records of the Hong Kong Hospital Authority (HA) CMS, economic modelling and serial cross-sectional surveys on health service use. This study includes people aged ≥18 years who have a documented diagnosis of diabetes mellitus, hypertension, cardiovascular disease, cancer, chronic respiratory disease or chronic kidney disease with at least one attendance at the HA hospital or clinic between 1 January 2010 and 31 December 2019, and without COVID-19 infection. Changes in all-cause mortality, disease-specific outcomes, and health services use rates and costs will be assessed between pre-COVID-19 and-post-COVID-19 pandemic or during each wave using an interrupted time series analysis. The long-term health economic impact of healthcare disruptions during the COVID-19 pandemic will be studied using microsimulation modelling. Multivariable Cox proportional hazards regression and Poisson/negative binomial regression will be used to evaluate the effect of different modes of supplementary care on health outcomes. ETHICS AND DISSEMINATION The study was approved by the institutional review board of the University of Hong Kong, the HA Hong Kong West Cluster (reference number UW 21-297). The study findings will be disseminated through peer-reviewed publications and international conferences.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Noncommunicable Diseases / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Adolescent / Adult / Humans Language: English Journal: BMJ Open Year: 2022 Document Type: Article Affiliation country: Bmjopen-2022-063150

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Noncommunicable Diseases / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Adolescent / Adult / Humans Language: English Journal: BMJ Open Year: 2022 Document Type: Article Affiliation country: Bmjopen-2022-063150