Mesenchymal stem cells and their derived small extracellular vesicles for COVID-19 treatment.
Stem Cell Res Ther
; 13(1): 410, 2022 08 12.
Article
in English
| MEDLINE | ID: covidwho-1993380
ABSTRACT
Since December 2019, the coronavirus (COVID-19) pandemic has imposed huge burdens to the whole world, seriously affecting global economic growth, and threatening people's lives and health. At present, some therapeutic regimens are available for treatment of COVID-19 pneumonia, including antiviral therapy, immunity therapy, anticoagulant therapy, and others. Among them, injection of mesenchymal stem cells (MSCs) is currently a promising therapy. The preclinical studies and clinical trials using MSCs and small extracellular vesicles derived from MSCs (MSC-sEVs) in treating COVID-19 were summarized. Then, the molecular mechanism, feasibility, and safety of treating COVID-19 with MSCs and MSC-sEVs were also discussed.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Coronavirus Infections
/
Mesenchymal Stem Cell Transplantation
/
Mesenchymal Stem Cells
/
Extracellular Vesicles
/
COVID-19
/
COVID-19 Drug Treatment
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Stem Cell Res Ther
Year:
2022
Document Type:
Article
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