Comparison of Clonazepam and Tongue Protector in the Treatment of Burning Mouth Syndrome.
Int J Environ Res Public Health
; 19(15)2022 07 24.
Article
in English
| MEDLINE | ID: covidwho-1994028
ABSTRACT
BACKGROUND:
BMS is a chronic pain syndrome affecting the oral mucosa. It consists of experiencing a burning or dysesthetic sensation. BMS prevalence varies, with up to 15% among women. An effective treatment is still unattainable. MATERIAL ANDMETHODS:
A total of 60 patients with BMS qualified for a randomised trial, divided in two groups the clonazepam-treated and tongue protector group. Treatment was provided for 4 weeks in both groups. In the former, the oral dosage of clonazepam 0.5 mg; in the latter, a tongue protector was used. Clinical oral examination was performed, and the presence of taste disorder and pain intensity, on the visual analogues scale, were recorded. Psychological domains were explored with the Beck depression inventory (depression), Athens insomnia scale (insomnia), Eyesenck personality questionnaire-revised (personality traits), and WHO quality of life questionnaire (quality of life).RESULTS:
Complete recovery was observed in three patients after clonazepam and one patient after tongue guard treatment. A greater improvement in the VAS scores, from baseline to the control values, was demonstrated in the clonazepam group, and it was statistically significant. In women, the level of depression significantly correlated with all domains of quality of life.CONCLUSIONS:
BMS is an ongoing multi-specialist challenge. The development of new pathophysiological concepts of BMS offers hope for more effective treatment. Considering the influence of BMS on the quality of life and mental disorders in most patients, further research on the possibilities of therapy seems to be very important.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Burning Mouth Syndrome
/
Sleep Initiation and Maintenance Disorders
Type of study:
Diagnostic study
/
Experimental Studies
/
Observational study
/
Prognostic study
/
Qualitative research
/
Randomized controlled trials
Limits:
Female
/
Humans
Language:
English
Year:
2022
Document Type:
Article
Affiliation country:
Ijerph19158999
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