Effect of HSP90AB1 on the replication of avian infectious bronchitis virus
Chinese Veterinary Science / Zhongguo Shouyi Kexue
; 50(9):1112-1118, 2020.
Article
in Chinese
| CAB Abstracts | ID: covidwho-1994653
ABSTRACT
The effects of heat shock protein HSPQOABl on the replication of avian infectious bronchitis virus(AIBV) were confirmed by using over expression and RNA interference methods. The results showed that over expression of HSPQOABI inhibited AIBV replication, whereas knockdown of HSPQOABl in- creased AIBV replication. These results indicated that HSPQOABI is a potential anti-viral host factor. These findings provide the basis for further study of the pathogenic mechanism of AIBV and anti-coronavirus infection.
Host Resistance and Immunity [HH600]; Animal Immunology [LL650]; Prion, Viral, Bacterial and Fungal Pathogens of Animals [LL821]; Molecular Biology and Molecular Genetics [ZZ360]; Biochemistry and Physiology of Microorganisms [ZZ394]; Genetics and Molecular Biology of Microorganisms [ZZ395]; antiviral properties; disease resistance; gene expression; heat shock proteins; pathogenesis; RNA; severe acute respiratory syndrome; viral diseases; viral replication; virulence; avian infectious bronchitis; Infectious bronchitis virus; viruses; Avian coronavirus; Gammacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; anti-viral properties; resistance to disease; IBV infection; ribonucleic acid; SARS; viral infections
Full text:
Available
Collection:
Databases of international organizations
Database:
CAB Abstracts
Type of study:
Experimental Studies
Language:
Chinese
Journal:
Zhongguo Shouyi Kexue
Year:
2020
Document Type:
Article
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