HUBUNGAN KADAR C-REAKTIV PROTEIN (CRP) DENGAN NILAI CYCLE TRESHOLD (CT) PADA PENDERITA COVID-19

ABSTRACT

Background: COVID-19 infection is caused by a coronavirus, with the main symptoms being respiratory problems. Common diagnostic tests performed are rapid antigen test, antibody rapid test, ELISA and RT-PCR. The gold standard test for diagnosing COVID-19 is RT-PCR. Another recommended parameter is viral load, namely the cycle threshold value. CRP is one of the parameters for examining inflammation markers in COVID-19 cases. C-Reactive Protein levels can be used for the initial diagnosis of pneumonia. Patients with severe pneumonia have elevated levels of C-Reactive Protein. The purpose of this study was to determine the correlation of the Cycle threshold value with levels of C-Reactive Protein, in patients with COVID-19. The type of research conducted is correlational, nonexperimental quantitative. The research was conducted at the Charitas Hospital KM.7 Palembang Hospital Laboratory from May to June 2020. The research subjects were 40 patients at Charitas Hospital KM.7. The statistical test used was the Pearson correlation test, and the test results obtained a sig value of 0.494 (p>0.05). The conclusion is that there is no relationship between Cycle Threshold values and C-Reactive Protein levels in COVID-19 patients. (English) [ FROM AUTHOR] Latar Belakang Infeksi COVID-19 disebabkan oleh virus corona, dengan gejala utama berupa gangguan pernapasan. Pemeriksaan diagnostik yang umum dilakukan yaitu rapid test antigen, rapid test antibodi, ELISA dan RT-PCR. Pemeriksaan baku emas untuk mendiagnosis COVID-19 adalah RT-PCR. Parameter lain yang disarankan adalah viral load yaitu nilai Cycle treshold. CRP merupakan salah satu parameter pemeriksaan penanda inflamasi pada kasus COVID-19. Kadar C-Reaktif Protein dapat digunakan untuk diagnosis awal pneumonia. Pasien dengan pneumonia berat terjadi peningkatan kadar C-Reaktif Protein yang tinggi. Tujuan penelitian ini untuk mengetahui korelasi nilai Cycle threshold dengan kadar CReaktif Protein, pada penderita COVID-19. Jenis penelitian yang dilakukan adalah kuantitatif non eksperimental korelasional, penelitian dilakukan di Laboratorium Rumah Sakit Charitas Hospital KM.7 Palembang pada bulan Mei s/d Juni 2020. Subjek penelitian adalah pasien rawat inap di Rumah Sakit Charitas Hospital KM.7 sebanyak 40 orang. Uji statistik yang digunakan uji korelasi pearson, hasil uji didapatkan nilai sig 0,494 (p > 0,05). Kesimpulan tidak terdapat hubungan antara nilai Cycle treshold dan kadar C-Reaktif Protein pada penderita COVID-19. (Indonesian) [ FROM AUTHOR] Copyright of Journal of Syntax Literate is the property of Ridwan Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)