P53 in endothelial function and unfolded protein response regulation.
Cell Biol Int
; 46(12): 2257-2261, 2022 Dec.
Article
in English
| MEDLINE | ID: covidwho-1999839
ABSTRACT
Vascular barrier dysfunction due to endothelial hyperpermeability has been associated with the pathophysiology of sepsis and severe lung injury, which may inflict acute respiratory distress syndrome (ARDS). Our group is focused on the mechanisms operating towards the regulation of endothelial permeability, to contribute in the development of efficient and targeted countermeasures against ARDS. Unfortunately, the number of ARDS-related deaths in the intensive care units has dramatically increased during the COVID-19 era. The findings described herein inform the corresponding scientific and medical community on the relation of P53 and stress responses in barrier function.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Respiratory Distress Syndrome
/
Sepsis
/
COVID-19
Limits:
Humans
Language:
English
Journal:
Cell Biol Int
Year:
2022
Document Type:
Article
Affiliation country:
Cbin.11891
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