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Toxic epidermal necrolysis after first dose of Pfizer-BioNTech (BNT162b2) vaccination with pharmacogenomic testing.
Siripipattanamongkol, Nunthana; Rattanasak, Sirawich; Taiyaitieng, Chanya; Inthajak, Yanapha; Kuawatcharawong, Nitchamon; Sukasem, Chonlaphat; Tempark, Therdpong.
  • Siripipattanamongkol N; Departments of Pediatrics, Chiangrai Prachanukroh Hospital, Chiangrai, Thailand.
  • Rattanasak S; Departments of Pediatrics, Chiangrai Prachanukroh Hospital, Chiangrai, Thailand.
  • Taiyaitieng C; Departments of Medicine, Chiangrai Prachanukroh Hospital, Chiangrai, Thailand.
  • Inthajak Y; Departments of Ophthalmology, Chiangrai Prachanukroh Hospital, Chiangrai, Thailand.
  • Kuawatcharawong N; Departments of Surgery, Chiangrai Prachanukroh Hospital, Chiangrai, Thailand.
  • Sukasem C; Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
  • Tempark T; Pharmacogenomics and Precision Medicine Clinic, The Preventive Genomics & Family Check-up Services Center, Bumrungrad International Hospital, Bangkok, Thailand.
Pediatr Dermatol ; 39(4): 601-605, 2022 Jul.
Article in English | MEDLINE | ID: covidwho-2001730
ABSTRACT
Toxic epidermal necrolysis (TEN) is a rare and acute life-threatening condition and one of the severe cutaneous adverse drug reactions. There are limited data on TEN from the COVID-19 vaccine regarding its pathogenesis, treatment, and prognosis, particularly in children. We report a case of COVID-19 vaccine-induced TEN and the patient's human leukocyte antigen pharmacogenomic profile.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Stevens-Johnson Syndrome / COVID-19 Vaccines / COVID-19 Type of study: Case report / Observational study / Prognostic study Topics: Vaccines Limits: Child / Humans Language: English Journal: Pediatr Dermatol Year: 2022 Document Type: Article Affiliation country: Pde.15074

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Stevens-Johnson Syndrome / COVID-19 Vaccines / COVID-19 Type of study: Case report / Observational study / Prognostic study Topics: Vaccines Limits: Child / Humans Language: English Journal: Pediatr Dermatol Year: 2022 Document Type: Article Affiliation country: Pde.15074