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Edible vaccines: a nutritional substitute for traditional immunization
Pharmacognosy Reviews ; 16(32):62-69, 2022.
Article in English | CAB Abstracts | ID: covidwho-2002632
ABSTRACT
Edible vaccines are created from transgenic plants and animals and contain immunostimulant. Edible vaccines, to put it simply, are medications generated from plants or animals. In underdeveloped countries, oral vaccines are less expensive and more widely available. Researchers came up with the idea of edible vaccines, in which edible plant pieces are employed as a vaccine factory. To make edible vaccinations, scientists put desired genes into plants and then force the plants to generate the proteins expressed in the genes. Transgenic plants are the result of transformation, whereas transformation is the act of converting plants. The edible vaccination promotes mucosal immunity. Dendritic cells in the gut can assist native T cells activate and differentiate into follicular T-helpers (Tfh). T and B cells will respond precisely to a reliable, digestible immunization. Potato, tomato, banana, carrots, tobacco, papaya, algae, and a variety of other plants are utilised as alternative agents for standard vaccinations. Malaria, cholera, hepatitis, rabies, measles, rotavirus, diarrhoea cancer treatments and treatment of covid-19 are among the illnesses for which plant-based vaccines have been created. It takes time and dedication to develop and sell edible vaccinations. Many edible vaccines for animal and human ailments have been developed and have gone through various levels of clinical testing. The importance of plant-based vaccinations is emphasized in this article.
Keywords
Horticultural Crops [FF003]; Field Crops [FF005]; Plant Breeding and Genetics [FF020]; Host Resistance and Immunity [HH600]; Human Immunology and Allergology [VV055]; Prion, Viral, Bacterial and Fungal Pathogens of Humans [VV210]; Animal and in vitro Models for Pharmaceuticals [VV450]; Genetic Engineering, Gene Transfer and Transgenics [WW100]; vaccines; immunization; transgenic plants; genes; gene expression; genetic transformation; genetic engineering; immunity; vaccination; mucosa; T lymphocytes; B lymphocytes; potatoes; tomatoes; bananas; carrots; tobacco; pawpaws; malaria; cholera; hepatitis; rabies; measles; diarrhoea; neoplasms; coronavirus disease 2019; viral diseases; reviews; plant proteins; medicinal plants; genetically engineered organisms; aquatic plants; aquatic organisms; protozoal infections; parasites; infections; parasitoses; bacterial diseases; immune sensitization; Solanum tuberosum; Solanum lycopersicum; Musa; Daucus carota; Nicotiana; Carica papaya; algae; Rotavirus; Severe acute respiratory syndrome coronavirus 2; plants; Plasmodium; Solanum; Solanaceae; Solanales; eudicots; angiosperms; Spermatophyta; eukaryotes; Musaceae; Zingiberales; commelinids; monocotyledons; Daucus; Apiaceae; Apiales; Carica; Caricaceae; Brassicales; Sedoreovirinae; Reoviridae; dsRNA Viruses; RNA Viruses; viruses; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; Plasmodiidae; Haemospororida; Apicomplexa; Protozoa; genetically engineered plants; genetically modified plants; GMOs; genetic manipulation; mucous membrane; T cells; B cells; Lycopersicon esculentum; papayas; diarrhea; scouring; cancers; SARS-CoV-2; viral infections; drug plants; medicinal herbs; officinal plants; genetically modified organisms; GEOs; aquatic species; protozoal diseases; parasitosis; parasitic diseases; parasitic infestations; bacterial infections; bacterioses; bacterium

Full text: Available Collection: Databases of international organizations Database: CAB Abstracts Topics: Vaccines Language: English Journal: Pharmacognosy Reviews Year: 2022 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: CAB Abstracts Topics: Vaccines Language: English Journal: Pharmacognosy Reviews Year: 2022 Document Type: Article