Post-marketing safety evaluation of flu vaccine during the 2020-2021 flu vaccination campaign in Italy: a Self-Controlled Case Series study of Guillain-Barre syndrome
Inserto BEN Bollettino Epidemiologico Nazionale
; 3(2):1-9, 2022.
Article
in Italian
| GIM | ID: covidwho-2002913
ABSTRACT
Introduction:
The Istituto Superiore di Sanita and the Agenzia Italiana del Farmaco coordinate the project TheShinISS-Vax, Flu, a post-marketing "active" surveillance of influenza vaccines. We report the results of the investigation using the Self- Controlled Case Series (SCCS) design on influenza vaccine and Guillain-Barre syndrome in vaccinated population aged over than 6 months, during the influenza vaccine campaign 2020-2021 in Italy. Materials andmethods:
A SCCS multi-regional study was carried out using linked data from Regional Health Care Registries of Valle d'Aosta, Friuli Venezia Giulia, Emilia-Romagna, Toscana, Lazio, Campania, and Puglia. Relative incidence of Guillain-Barre syndrome was estimated, comparing the exposure risk periods (0-41 days from the vaccination day, subdivided in six intervals) with the unexposed period.
immunization; vaccination; vaccines; human diseases; influenza; influenza viruses; Guillain-Barre syndrome; risk factors; disease prevention; health protection; safety; marketing; viral diseases; campaigns; public health; case studies; disease incidence; epidemiology; risk; exposure; hospital admission; complications; mortality; immune sensitization; man; Severe acute respiratory syndrome coronavirus 2; Orthomyxoviridae; Italy; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; eukaryotes; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; European Union Countries; high income countries; Mediterranean Region; OECD Countries; Southern Europe; Europe; very high Human Development Index countries; negative-sense ssRNA Viruses; flu; SARS-CoV-2; viral infections; death rate
Full text:
Available
Collection:
Databases of international organizations
Database:
GIM
Type of study:
Experimental Studies
Topics:
Vaccines
Language:
Italian
Journal:
Inserto BEN Bollettino Epidemiologico Nazionale
Year:
2022
Document Type:
Article
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