COVID-19 Clinical Characteristics and Outcomesin Children Aged </=16 Years at theUniversityHospital ofthe WestIndies, Jamaica in 2020-2021
Pediatrics
; 149, 2022.
Article
in English
| EMBASE | ID: covidwho-2003015
ABSTRACT
Background:
By June 1, 2021, Jamaica recorded 48,639 RT-PCR confirmed SARS-CoV-2 cases and 951 deaths, with a case fatality rate of 2%. Children <18 years comprised 10.3% (4,999) of cases and 0.1% and 0.2% deaths in <10 and 10-18 year age-groups, respectively. Community transmission is ongoing, having been declared September 2020.Methods:
Ambispective case series describing clinical characteristics and outcomes of COVID-19 in children aged.Results:
Seventy-nine children aged 4 abnormal inflammatory biomarkers (13/72%) including D-dimers, Creactive protein, ESR, ferritin, troponins, lactate dehydrogenase, neutrophils, platelets, lymphocytes, albumen . MISC-positive cases were treated with intravenous immune gammaglobulin (78% vs. 0%;p < 0.01), aspirin (68% vs. 0%;p < 0.01) and steroids (50% vs. 9%;p = 0.003). MISC-positive cases had intensive care admissions (two), non-invasive ventilation (two) and inotropes/vasopressor support (none). Outcomes included readmission for MISC-related neurological complications two(5%), discharged with one month follow-up 39(95%), transferred one(2.4%) and demise from myocardial complications in a child with premorbid end-stage renal disease and haemodialysis one(2.4%).Conclusion:
More than half of the children aged.
acetylsalicylic acid; biological marker; C reactive protein; D dimer; endogenous compound; ferritin; hypertensive factor; immunoglobulin; inotropic agent; lactate dehydrogenase; steroid; troponin; adolescent; adult; case fatality rate; case study; child; clinical feature; community transmission; complication; conference abstract; coronavirus disease 2019; end stage renal disease; female; follow up; groups by age; hemodialysis; hospital readmission; human; human cell; intensive care; intravenous drug administration; Jamaica; lymphocyte; major clinical study; male; neurological complication; neutrophil; nonhuman; noninvasive ventilation; outcome assessment; preschool child; Severe acute respiratory syndrome coronavirus 2; thrombocyte
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Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Prognostic study
Country/Region as subject:
English Caribbean
/
Jamaica
Language:
English
Journal:
Pediatrics
Year:
2022
Document Type:
Article
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