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SARS-CoV-2 Infections in Vaccinated and Unvaccinated Populations in Camp Lemonnier, Djibouti, from April 2020 to January 2022.
Arnold, Catherine E; Voegtly, Logan J; Stefanov, Emily K; Lueder, Matthew R; Luquette, Andrea E; Miller, Robin H; Miner, Haven L; Bennett, Andrew J; Glang, Lindsay; McGinnis, Tara N; Reisinger, Kristie E; Dugan, Jae W; Mangat, Michael A; Silberger, Daniel J; Pavlicek, Rebecca L; Watters, Chaselynn M; Rice, Gregory K; Malagon, Francisco; Cer, Regina Z; Eggan, Stephen M; Bishop-Lilly, Kimberly A.
  • Arnold CE; Naval Medical Research Center, Fort Detrick, Frederick, MD 21702, USA.
  • Voegtly LJ; Defense Threat Reduction Agency, Fort Belvoir, VA 22060, USA.
  • Stefanov EK; Naval Medical Research Center, Fort Detrick, Frederick, MD 21702, USA.
  • Lueder MR; Leidos, Reston, VA 20190, USA.
  • Luquette AE; U.S. Naval Medical Research Unit No. 3 (NAMRU-3), 95030 Sigonella, Italy.
  • Miller RH; Naval Medical Research Center, Fort Detrick, Frederick, MD 21702, USA.
  • Miner HL; Leidos, Reston, VA 20190, USA.
  • Bennett AJ; Naval Medical Research Center, Fort Detrick, Frederick, MD 21702, USA.
  • Glang L; Leidos, Reston, VA 20190, USA.
  • McGinnis TN; Naval Medical Research Center, Fort Detrick, Frederick, MD 21702, USA.
  • Reisinger KE; Leidos, Reston, VA 20190, USA.
  • Dugan JW; Naval Medical Research Center, Fort Detrick, Frederick, MD 21702, USA.
  • Mangat MA; Leidos, Reston, VA 20190, USA.
  • Silberger DJ; Naval Medical Research Center, Fort Detrick, Frederick, MD 21702, USA.
  • Pavlicek RL; Leidos, Reston, VA 20190, USA.
  • Watters CM; Naval Medical Research Center, Fort Detrick, Frederick, MD 21702, USA.
  • Rice GK; Leidos, Reston, VA 20190, USA.
  • Malagon F; Expeditionary Medical Facility, CLDJ-HOA, Camp Lemonnier 09622, Djibouti.
  • Cer RZ; Naval Medical Research Center, Fort Detrick, Frederick, MD 21702, USA.
  • Eggan SM; Expeditionary Medical Facility, CLDJ-HOA, Camp Lemonnier 09622, Djibouti.
  • Bishop-Lilly KA; U.S. Naval Medical Research Unit No. 3 (NAMRU-3), 95030 Sigonella, Italy.
Viruses ; 14(9)2022 08 30.
Article in English | MEDLINE | ID: covidwho-2006228
ABSTRACT
The global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has highlighted the disparity between developed and developing countries for infectious disease surveillance and the sequencing of pathogen genomes. The majority of SARS-CoV-2 sequences published are from Europe, North America, and Asia. Between April 2020 and January 2022, 795 SARS-CoV-2-positive nares swabs from individuals in the U.S. Navy installation Camp Lemonnier, Djibouti, were collected, sequenced, and analyzed. In this study, we described the results of genomic sequencing and analysis for 589 samples, the first published viral sequences for Djibouti, including 196 cases of vaccine breakthrough infections. This study contributes to the knowledge base of circulating SARS-CoV-2 lineages in the under-sampled country of Djibouti, where only 716 total genome sequences are available at time of publication. Our analysis resulted in the detection of circulating variants of concern, mutations of interest in lineages in which those mutations are not common, and emerging spike mutations.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccines / COVID-19 Type of study: Observational study Topics: Vaccines / Variants Limits: Humans Country/Region as subject: Africa Language: English Year: 2022 Document Type: Article Affiliation country: V14091918

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccines / COVID-19 Type of study: Observational study Topics: Vaccines / Variants Limits: Humans Country/Region as subject: Africa Language: English Year: 2022 Document Type: Article Affiliation country: V14091918