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Clinical Spectrum of CMV Infection in Post COVID-19 Rehospitalized Patients: A Retrospective Analysis and Review of Literature
Indian Journal of Critical Care Medicine ; 26:S84, 2022.
Article in English | EMBASE | ID: covidwho-2006372
ABSTRACT
Cytomegalovirus infection is a common occurrence in the immunocompromised host and can affect any organ of the human body. Clinical presentation is extremely variable and nonspecific, which makes diagnosis difficult. Post COVID patients are immunocompromised due to viral infection, uncontrolled diabetes, poor nutrition, hyper-catabolic state, and use of immunosuppressive drugs like steroids and tocilizumab. We are presenting a clinical spectrum of seven post COVID patients who were readmitted to the hospital with variable clinical spectrums. Early suspicion and appropriate pharmacological interventions were necessary to make the right diagnosis and achieve a positive outcome. Materials and

methods:

This is a retrospective analysis of seven post COVID patients admitted in our hospital since 15th January to 1 August 2021. All post COVID patients were investigated and only those were positive by PCR and serology for CMV was analyzed.

Results:

All seven patients were previously treated in hospital for severe COVID associated pneumonia and readmitted with various CMV related complications. Three out of seven patients died and four survived. All patients were having multisystem involvement with predominantly affected respiratory system in the form of pneumonia and reappearance of ground glass lesions in HRCT and increased demand of oxygen.

Conclusion:

CMV-associated complications are underdiagnosed in post COVID patients and this is one of the etiologies of re-hospitalization of such patients. Clinical spectrum is wide and nonspecific therefore strong clinical suspicion and early investigation can provide an opportunity for optimal therapeutic intervention for the suffering patient.
Keywords

Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Observational study / Prognostic study Topics: Long Covid Language: English Journal: Indian Journal of Critical Care Medicine Year: 2022 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Observational study / Prognostic study Topics: Long Covid Language: English Journal: Indian Journal of Critical Care Medicine Year: 2022 Document Type: Article