Challenges in diagnostic research of multisystem inflammatory syndrome in children associated with COVID-19 in combination with the early stage of Epstein-Barr virus infection
Children Infections
; 21(2):51-56, 2022.
Article
in Russian
| EMBASE | ID: covidwho-2006683
ABSTRACT
Multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 is a rare life-threatening immunopathological complication of COVID-19 that develops 1-6 weeks after the acute coronavirus infection. MIS-C is characterized by fever and multiorgan inflammation. We present a clinical case of a 10-year-old boy with skin lesions at the onset of MIS-C (erythematous malar rash, lacelike rash on the trunk and extremities and petechiae) with macrophage activation syndrome development and the early stage of primary Epstein-Barr virus infection (EBV infection) which required the exclusion of X-linked lymphoproliferative disease. This clinical case demonstrates the complexity of diagnosis in MIS-C with skin manifestations at the onset of the disease, especially with concurrent activation of other infections, particularly EBV infection.
article; case report; child; clinical article; coronavirus disease 2019; Epstein Barr virus; Epstein Barr virus infection; human; limb; lymphoproliferative disease; macrophage activation syndrome; malar rash; male; nonhuman; pediatric multisystem inflammatory syndrome; petechia; rash; school child; skin defect; skin manifestation; trunk
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Language:
Russian
Journal:
Children Infections
Year:
2022
Document Type:
Article
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