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Luminescence nanomaterials for biosensing applications.
Kumar, Vaneet; Bhatt, Diksha; Pandey, Sadanand.
  • Kumar V; School of Natural Science, CT University, Ludhiana, Punjab, India.
  • Bhatt D; School of Natural Science, CT University, Ludhiana, Punjab, India.
  • Saruchi; Department of Biotechnology, CT Institute of Pharmaceutical Sciences (CTIPS), CT Group of Institutions, Shahpur Campus, Jalandhar, Punjab, India.
  • Pandey S; Department of Chemistry, College of Natural Science, Yeungnam University, 280 Daehak-Ro, Gyeongsan, Gyeongbuk, Republic of Korea.
Luminescence ; 2022 Aug 30.
Article in English | MEDLINE | ID: covidwho-2007090
ABSTRACT
Due to their capacity to immobilize more bioreceptor parts at reduced volumes, nanomaterials have emerged as potential tools for increasing the sensitivity to specific molecules. Furthermore, carbon nanotubes, gold nanoparticles, polymer nanoparticles, semiconductor quantum dots, nanodiamonds, and graphene are among the nanomaterials that are under investigation. Due to the fast development of this field of research, this review summarizes the classification of biosensors using the main receptors and design of biosensors. Numerous studies have concentrated on the manipulation of persistent luminescence nanoparticles (PLNPs) in biosensing, cell tracking, bioimaging, and cancer therapy due to the effective removal of autofluorescence interference from tissues and the ultra-long near-infrared afterglow emission. As luminescence has a unique optical property, it can be detected without constant external illumination, preventing autofluorescence and light dispersion through tissues. These successes have sparked an increasing interest in creating novel PLNP types with the desired superior properties and multiple applications. In this review, we emphasize the most recent developments in biosensing, imaging, and image-guided therapy whilst summarizing the research on synthesis methods, bioapplications, biomembrane modification, and the biosafety of PLNPs. Finally, the remaining issues and difficulties are examined together with prospective future developments in the biomedical application field.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Language: English Journal subject: Biophysics / Biochemistry Year: 2022 Document Type: Article Affiliation country: Bio.4373

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Language: English Journal subject: Biophysics / Biochemistry Year: 2022 Document Type: Article Affiliation country: Bio.4373