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Citicoline and COVID-19: vis-à-vis conjectured.
Al-Kuraishy, Hayder M; Al-Buhadily, Ali K; Al-Gareeb, Ali I; Alorabi, Mohammed; Hadi Al-Harcan, Nasser A; El-Bouseary, Maisra M; Batiha, Gaber El-Saber.
  • Al-Kuraishy HM; Department of Clinical Pharmacology and Medicine, College of Medicine, Al-Mustansiriya University, Baghdad, Iraq.
  • Al-Buhadily AK; Department of Clinical Pharmacology and Medicine, College of Medicine, Al-Mustansiriya University, Baghdad, Iraq.
  • Al-Gareeb AI; Department of Clinical Pharmacology and Medicine, College of Medicine, Al-Mustansiriya University, Baghdad, Iraq.
  • Alorabi M; Department of Biotechnology, College of Sciences, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia.
  • Hadi Al-Harcan NA; Department of Clinical Pharmacology and Medicine, College of Medicine, Al-Rasheed University College, Baghdad, Iraq.
  • El-Bouseary MM; Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Tanta University, Tanta, Egypt. maysra_mohamed@pharm.tanta.edu.eg.
  • Batiha GE; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, AlBeheira, Damanhour, 22511, Egypt. gaberbatiha@gmail.com.
Naunyn Schmiedebergs Arch Pharmacol ; 395(12): 1463-1475, 2022 12.
Article in English | MEDLINE | ID: covidwho-2248676
ABSTRACT
Coronavirus disease 2019 (COVID-19) is a current pandemic disease caused by a novel severe acute respiratory syndrome coronavirus virus respiratory type 2 (SARS-CoV-2). SARS-CoV-2 infection is linked with various neurological manifestations due to cytokine-induced disruption of the blood brain barrier (BBB), neuroinflammation, and peripheral neuronal injury, or due to direct SARS-CoV-2 neurotropism. Of note, many repurposed agents were included in different therapeutic protocols in the management of COVID-19. These agents did not produce an effective therapeutic eradication of SARS-CoV-2, and continuing searching for novel anti-SARS-CoV-2 agents is a type of challenge nowadays. Therefore, this study aimed to review the potential anti-inflammatory and antioxidant effects of citicoline in the management of COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Drug Treatment Limits: Humans Language: English Journal: Naunyn Schmiedebergs Arch Pharmacol Year: 2022 Document Type: Article Affiliation country: S00210-022-02284-6

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Drug Treatment Limits: Humans Language: English Journal: Naunyn Schmiedebergs Arch Pharmacol Year: 2022 Document Type: Article Affiliation country: S00210-022-02284-6