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COVID-19 in patients with B cell immune deficiency.
Vergidis, Paschalis; Levy, Emily R; Ristagno, Elizabeth H; Iyer, Vivek N; O'Horo, John C; Joshi, Avni Y.
  • Vergidis P; Division of Public Health, Infectious Diseases and Occupational Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
  • Levy ER; Division of Pediatric Critical Care Medicine, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA; Division of Pediatric Infectious Diseases, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
  • Ristagno EH; Division of Pediatric Infectious Diseases, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
  • Iyer VN; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA.
  • O'Horo JC; Division of Public Health, Infectious Diseases and Occupational Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA.
  • Joshi AY; Division of Pediatric and Adult Allergy and Immunology, Mayo Clinic, Rochester, MN, USA. Electronic address: Joshi.Avni@mayo.edu.
J Immunol Methods ; 510: 113351, 2022 Nov.
Article in English | MEDLINE | ID: covidwho-2285439
ABSTRACT
This article aims to describe the clinical manifestations and management of COVID-19 in patients with primary and secondary B cell deficient states. We describe the epidemiologic and clinical features as well as unique management paradigm including isolation precautions with COVID-19. We then focus upon primary and secondary preventive approaches including vaccination and pre- as well as post-exposure prophylaxis. Further, we elaborate upon the important disease specific risk factors in these patients and the need to conduct prospective clinical trials to develop individualized management strategies in this population.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: J Immunol Methods Year: 2022 Document Type: Article Affiliation country: J.jim.2022.113351

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: J Immunol Methods Year: 2022 Document Type: Article Affiliation country: J.jim.2022.113351