Incidence and risk factors for stroke in patients with COVID-19 in the Philippines: An analysis of 10,881 cases.
J Stroke Cerebrovasc Dis
; 31(11): 106776, 2022 Nov.
Article
in English
| MEDLINE | ID: covidwho-2007885
ABSTRACT
BACKGROUND:
While most large studies on the possible association of COVID-19 and stroke were done in high-income countries, only a few studies consisting of small sample populations have been done in low- to middle-income countries like the Philippines.OBJECTIVES:
To determine the risk factors of stroke among hospitalized COVID19 patients in the Philippines; to determine the possible association between these risk factors and stroke among the same cohort; and to determine if there is an association between mortality and stroke in this same group.METHODOLOGY:
We obtained relevant clinical and neurological, including stroke data from the Philippine CORONA study, an observational study involving 10,881 patients with COVID-19 admitted in 37 referral hospitals from all over the Philippines.RESULTS:
The incidence of stroke among patients with COVID-19 was 3.4% (n = 367). There were more deaths among patients with stroke and COVID-19 than those without stroke and COVID-19 (42.2% vs 14.7%, p < 0.01). In addition, more patients with stroke were admitted in the ICU (43.3% vs 15.0%, p < 0.01) regardless of cause. Smoking (OR 1.5, 95% CI 1.3 to 1.7, p < 0.0001), hypertension (OR1.75, 95% CI1.53 to 1.97, p < 0.0001), presence of heart failure (OR 1.4, 95% CI 1.07 to 1.86, p = 0.01), presence of any neurologic co-morbidities (OR 1.4, 95% CI1.11 to 1.46, p = 0.004), and history of stroke (OR2.3, 95% CI1.82 to 2.97, p < 0.0001) had direct significant correlation with stroke; while being a health care worker (OR 0.5, 95% CI 0.33 to 0.70, p < 0.0004) had an inverse significant association with stroke.CONCLUSION:
COVID-19 stroke patients in the Philippines have a higher mortality and ICU admission rates than patients with COVID-19 alone or COVID-19 stroke patients from developed countries. Our cohort has similar cardiovascular and metabolic risk factors to western patients with stroke, highlighting that COVID-19 may only have a small contribution to stroke incidence.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Stroke
/
COVID-19
Type of study:
Cohort study
/
Diagnostic study
/
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
J Stroke Cerebrovasc Dis
Journal subject:
Vascular Diseases
/
Brain
Year:
2022
Document Type:
Article
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