Interrupted-time-series analysis of the immediate impact of COVID-19 mitigation measures on preterm birth in China.
Nat Commun
; 13(1): 5190, 2022 09 03.
Article
in English
| MEDLINE | ID: covidwho-2008278
ABSTRACT
Preliminary evidence from China and other countries has suggested that coronavirus disease 2019 (COVID-19) mitigation measures have caused a decline in preterm births, but evidence is conflicting. Utilising a national representative data of 11,714,947 pregnant women in China, we explored the immediate changes in preterm birth rates during the COVID-19 mitigation period using an interrupted-time-series analysis. We defined the period prior to February 1, 2020 as the baseline, followed by the COVID-19 mitigation stage. In the first month of the COVID-19 mitigation, a significant absolute decrease in preterm birth rates of 0.68% (95%CI-1.10% to -0.26%) in singleton, and of 2.80% (95%CI-4.51% to -1.09%) in multiple births was noted. This immediate decline in Wuhan was greater than that at the national level among singleton births [-2.21% (95%CI-4.09% to -0.34% vs. -0.68%)]. Here we report an immediate impact of COVID-19 mitigation measures on preterm birth in China.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Premature Birth
/
COVID-19
Type of study:
Experimental Studies
/
Observational study
Limits:
Female
/
Humans
/
Infant, Newborn
/
Pregnancy
Language:
English
Journal:
Nat Commun
Journal subject:
Biology
/
Science
Year:
2022
Document Type:
Article
Affiliation country:
S41467-022-32814-y
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