ARE PATIENTS with RA in REMISSION in FINLAND during the COVID TIMES? RESULTS from the FINNISH QUALITY REGISTER
Annals of the Rheumatic Diseases
; 81:1212, 2022.
Article
in English
| EMBASE | ID: covidwho-2008890
ABSTRACT
Background:
Worries have been expressed, concerning the care of chronic diseases during the Covid times (1).Objectives:
To study the current status of patients with RA in the Finnish quality register database.Methods:
Patients who receive care for RA were identifed in the database. Clinical and demographic data from the last visits during 2020-21 were collected, including swollen (SJC46) and tender joint counts (TJC46), doctor assessment of disease activity (Dr global), laboratory tests for infammatory and serology markers, patient reported outcomes (PROs), and DAS28. Regression models were applied to compare measures of clinical status between the health care regions, adjusted for gender, age, ACPA status, and disease duration.Results:
A total of 14163 patients (72% female, mean (SD) age 62 (14) years, median (IQR) disease duration 8.5 (2.6, 20) years, 84% ACPA positive) were identifed. For the entire population, the median (IQR) SJC46 was 0 (0, 1), TJC46 0 (0, 2), ESR 8 (5, 18), CRP 3 (1, 6), and dr global 8 (0, 19). Among PROs, median (IQR) HAQ was 0.5 (0, 1), pain 26 (10, 51), fatigue 28 (8, 54) and patient global 29 (11, 51). Between health care regions, statistically signifcant differences were found for all variables due to a large sample size. The mean (SD) DAS28 was 2.3 (0.9) for the entire group and 69 % of all patients had DAS28<2.6. The median DAS28 ranged from 2 to 2.7 among health care regions (Figure 1) (p<0.001). Majority of patients were taking csDMARDs only.Conclusion:
The quality register provides comprehensive real-world data on the current status of patients with RA. A majority of patients can be considered being in remission even during the Covid times.
cyclic citrullinated peptide antibody; endogenous compound; adult; conference abstract; coronavirus disease 2019; DAS28; demographics; fatigue; female; Finland; gender; Health Assessment Questionnaire; human; laboratory test; major clinical study; male; outcome assessment; pain; patient-reported outcome; regression model; remission; sample size; serology; tender joint count
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Annals of the Rheumatic Diseases
Year:
2022
Document Type:
Article
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