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Cardiac postacute sequelae symptoms of SARS-CoV-2 in community-dwelling adults: cross-sectional study
Open Heart ; 9(2), 2022.
Article in English | PMC | ID: covidwho-2009228
ABSTRACT

Objective:

To examine risk factors for cardiac-related postacute sequelae of SARS-CoV-2 infection (PASC) in community-dwelling adults after acute COVID-19 infection.

Methods:

We performed a cross-sectional analysis among adults who tested positive for COVID-19. Outcomes were self-reported cardiac-related PASC. We conducted stepwise multivariable logistic regression to assess association between the risk factors (existing cardiovascular disease (CVD), pre-existing conditions, days since positive test, COVID-19 hospitalisation, age, sex, education, income) and cardiac-related PASC.

Results:

In a sample of 442 persons, mean (SD) age was 45.4 (16.2) years, 71% were women, 13% were black, 46% had pre-existing conditions, 23% had cardiovascular (CV) risk factors and 4% had CVD. Prevalence of cardiac PASC was 43% and newly diagnosed cardiac conditions were 27%. The odds for cardiac-related PASC were higher among persons with underlying pre-existing conditions (adjusted OR (aOR) 2.00, 95% CI 1.28 to 3.10) and among those who were hospitalised (aOR 3.03, 95% CI 1.58 to 5.83).

Conclusions:

More than a third of persons with COVID-19 reported cardiac-related PASC symptoms. Underlying CVD, pre-existing diseases, age and COVID-19 hospitalisation are possible risk factors for cardiac-related PASC symptoms. COVID-19 may exacerbate CV risk factors and increase risk of complications.

Full text: Available Collection: Databases of international organizations Database: PMC Type of study: Observational study / Randomized controlled trials Topics: Long Covid Language: English Journal: Open Heart Year: 2022 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: PMC Type of study: Observational study / Randomized controlled trials Topics: Long Covid Language: English Journal: Open Heart Year: 2022 Document Type: Article