Cerebral venous sinus thrombosis-associated hemorrhage in vaccine-induced immune thrombotic thrombocytopenia: Catastrophic outcome if delayed diagnosis and treatment
Formosan Journal of Surgery
; 55(4):158-160, 2022.
Article
in English
| EMBASE | ID: covidwho-2010413
ABSTRACT
The authors reported the clinical course of a 58-year-old female suffering from cerebral venous sinus thrombosis associated with hemorrhage after the ChAdOx1 nCov-19 vaccination. Emergent decompressive craniectomy was performed, and aggressive blood transfusion was given. Nevertheless, progressive intracerebral hemorrhage and thrombocytopenia developed. A delayed diagnosis was made on a rare complication of vaccine-induced immune thrombotic thrombocytopenia (VITT) with a positive result of anti-platelet factor 4 antibodies (PF4 Ab). The patient died 4 days postoperative due to brainstem failure.
adult; article; blood transfusion; brain hemorrhage; brain stem; case report; cerebral sinus thrombosis; clinical article; complication; decompressive craniectomy; delayed diagnosis; diagnosis; female; human; middle aged; thrombocytopenia; treatment failure; vaccination; vaccine-induced immune thrombotic thrombocytopenia; endogenous compound; thrombocyte factor 4; vaxzevria
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Prognostic study
Topics:
Vaccines
Language:
English
Journal:
Formosan Journal of Surgery
Year:
2022
Document Type:
Article
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