Research progress of COVID-19 with acute kidney injury

ABSTRACT

COVID-19 is seriously endangering people's health and has become a global public crisis. The main target of the disease is the respiratory system. Acute respiratory distress syndrome and diffuse alveolar hemorrhage are the main clinical manifestations, which have aroused broad concern. However, SARS-CoV-2 involves multiple organs including the kidney. Acute renal injury caused by the virus is common, but is often underestimated or even overlooked. Acute renal injury is more common in critical patients with COVID-19 and is an independent risk factor for adverse prognosis. The latest research results at home and abroad on COVID-19 complicated with acute renal injury include epidemiology, risk factors, pathogenesis, pathological manifestations, prevention and treatment schemes, which help strengthen clinicians' understanding of acute renal injury, formulate targeted management strategies, and improve the overall prognosis of patients.