TumerNecrosis in COVID19 and Dibates

ABSTRACT

Background: The World Health Organization (WHO) and health authorities have devoted significant attention to understanding risk factors for coronavirus disease 19 (COVID-19) and their role in disease outcomes including tumer necrosis factor. In addition, diabetes may lead to lung dysfunction, such as decreased forced expiratory volume and forced vital capacity. Therefore, diabetes could possibly be a risk factor for covid-19. Our study aims to investigate the clinical characteristics of patients with severe covid-19 with diabetes mellitus, and the association of diabetes with the outcome in patients with severe covid-19. Materials and Methods: This study was carried out in a period between November 2021 and March 2022, blood was taken from patients (80) with covid-19. Samples were taken from patients who were present in Al-Zahraa teaching hospital in Iraq. A total of samples were subjected to laboratory examinations including Tumor necrosis factor α using specific ELISA Kit. Result: The result of this observational study was depending on the analysis of data from 80 COVID-19 patients. All selected sociodemographic features, disease indicators, and history of chronic disease were listed as frequencies and percentages. The mean age was 52 years old. The SPO2 for those patients was ranged from 79 to 95% with a mean equal to 90.10 ±3.48. All patients showed elevated CRP value with a mean = 83.52. More than half of the sample (52.5%) were females and near half of the (48.8%) were overweighted when calculate their BMI. The majority (92.5%) mentioned having no family history of diabetes mellitus and 95% of them have no any other diagnosed chronic disease. Near two thirds (67.5%) were prescribed steroid in the treatment regime for their COVID-19 infection. Mean difference of TNF was tested among positive Covid-19 having diabetic status, results showed that.