Safety of the live at attenuated vaccine avishield IB GI-13 against infectious bronchitis in SPF chickens during laying period
XIV. Simpozij peradarski dani
; 11(14):71-77, 2022.
Article
in English
| CAB Abstracts | ID: covidwho-2011268
ABSTRACT
Avian infectious bronchitis (IB) is an economically important, highly contagious, acute disease of Chickens caused by a single-stranded positive RNA Virus that belongs to the Coronaviridae family. The Virus can replicate in the oviduct and cause permanent damage in young hens resulting in the false layer occurrence. In laying hens, infectious bronchitis Virus (IBV) infections can cause a severe decline in egg production and a number of effects on egg quality and reduced hatchability. The most effective means of controlling IB in poultry is vaccination. In the areas with increased pressure of circulating field challenge Virus, live attenuated vaccines are also used during the laying period with the intention of keeping local protection of the respiratory tract at a high level. The vaccine strain IB V-173/11 contained in Avishield IB GI-13 vaccine is a strain that genetically (S1 gene) belongs to GI-13 lineage and antigenically to 793B IBV serotype. Viral infections of this serotype occur frequently in Europe and therefore most vaccination programs in broilers, layers and breeders along a live IBV vaccine of the Massachusetts serotype also include a live vaccine of the 793B serotype, GI-I3 lineage. In this paper, results of a safety evaluation of live attenuated IB vaccine strain V-173/11, when administered by spray method in a ten-fold maximum dose repeated by one maximum dose in 28-week-old specific pathogen free (SPF) layer Chickens are presented. As a control, non-vaccinated SPF layer chickens were included in the study. The vaccine is considered to be safe when used in laying period because no vaccinated chicken showed abnormal local or systemic reactions or signs of IB related disease, no chicken died from the causes attributable to the vaccine, egg quality was not altered, and there was no statistically significant difference in. egg production between the vaccinated and non-vaccinated group.
Host Resistance and Immunity [HH600]; Animal Immunology [LL650]; Prion, Viral, Bacterial and Fungal Pathogens of Animals [LL821]; Egg Producing Animals [LL130]; Eggs and Egg Products [QQ040]; vaccination; vaccines; live vaccines; hens; disease prevention; poultry; viral diseases; eggs; egg hatchability; immunization; RNA; disease control; germfree animals; attenuation; laboratory animals; avian infectious bronchitis; immune sensitization; Infectious bronchitis virus; fowls; birds; Massachusetts; USA; Avian coronavirus; Gammacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; Gallus gallus; Gallus; Phasianidae; Galliformes; vertebrates; Chordata; animals; eukaryotes; New England States of USA; Northeastern States of USA; APEC countries; high income countries; North America; America; OECD Countries; very high Human Development Index countries; IBV infection; chickens; attenuated vaccines; domesticated birds; United States of America; viral infections; hatchability; ribonucleic acid; pathogen-free animals
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Collection:
Databases of international organizations
Database:
CAB Abstracts
Topics:
Vaccines
Language:
English
Journal:
XIV. Simpozij peradarski dani
Year:
2022
Document Type:
Article
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