ADAPTABLE ENGINEERING OF CELLULOSE-BASED VERTICAL FLOW ASSAYS FOR RAPID DIAGNOSTICS - THE CASE OF COVID-19
25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
; : 857-858, 2021.
Article
in English
| Scopus | ID: covidwho-2012689
ABSTRACT
Paper microfluidics has had a rich history in medical diagnostics owing to their portability, low-cost and capacity for mass manufacture. While nitrocellulose has widespread use in commercial paper-based assays, shortages can become a bottleneck for deployment. Here, we seek to overcome this limitation by enabling swift and efficient production of cellulose-based paper assays with minimal substrate processing via protein engineering. We demonstrate good clinical and lab-based performance for both serological and antigen rapid tests and their compatibility with roll-to-roll mass manufacturing, which validates our proposed workflow for commercialization. © 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.
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Collection:
Databases of international organizations
Database:
Scopus
Language:
English
Journal:
25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Year:
2021
Document Type:
Article
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