A CENTRIFUGAL MICROFLUIDIC METHOD FOR ENRICHMENT AND ENZYMATIC EXTRACTION OF SARS-COV-2 RNA FROM CLINICAL SAMPLES
25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
; : 935-936, 2021.
Article
in English
| Scopus | ID: covidwho-2012751
ABSTRACT
The requirement for diversification of methods for sample preparation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is increasingly important to circumvent analysis bottlenecks and continue widespread surveillance testing. We report a centrifugally-driven microfluidic platform for automated affinity nanoparticle enrichment and enzymatic RNA extraction of SARS-CoV-2. The microfluidic disc (μCD) and accompanying mechatronic system(s) are capable of sample preparation from up to six patient samples simultaneously and under 20 minutes. © 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.
Affinity Enrichment; Centrifugal Microfluidics; Enzymatic Extraction; Reverse Transcription Polymerase Chain Reaction (RT-PCR); Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2); Centrifugation; Diseases; Extraction; Microfluidics; Polymerase chain reaction; RNA; Clinical samples; Microfluidic method; Microfluidic platforms; Reverse transcription polymerase chain reaction; Reverse transcription-polymerase chain reaction; Sample preparation; Severe acute respiratory syndrome coronavirus 2; Coronavirus
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Collection:
Databases of international organizations
Database:
Scopus
Type of study:
Prognostic study
Language:
English
Journal:
25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Year:
2021
Document Type:
Article
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