Case series of nebulizing r-tPA for COVID-19 induced acute respiratory distress syndrome.
Clin Case Rep
; 10(9): e6283, 2022 Sep.
Article
in English
| MEDLINE | ID: covidwho-2013434
ABSTRACT
Fibrin deposition in the alveolar spaces during pulmonary involvement of COVID-19 impairs the O2/CO2 exchange and leads to respiratory symptoms. In this report, Recombinant Tissue Plasminogen Activator (r-tPA) has been nebulized to 3 critically ill COVID-19 patients in order to resolve the deposited fibrin while avoiding the risk of bleeding. Based on these observations, nebulization of r-tPA may be a potential therapeutic approach and new area of research for future studies.
Full text:
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Collection:
International databases
Database:
MEDLINE
Type of study:
Case report
/
Observational study
/
Prognostic study
Language:
English
Journal:
Clin Case Rep
Year:
2022
Document Type:
Article
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