First importations of SARS-CoV-2 P.1 and P.2 variants from Brazil to Spain and early community transmission.
Enferm Infecc Microbiol Clin (Engl Ed)
; 40(5): 262-265, 2022 05.
Article
in English
| MEDLINE | ID: covidwho-2015163
ABSTRACT
INTRODUCTION:
SARS-CoV-2variants of concern (VOC) have been described in the UK (B.1.1.7), South Africa (B.1.351) and Brazil (P.1). Among them, the most scarce information has been obtained from the P.1 variant and more data on its global presence and about its spreading dynamics are needed.METHODS:
Whole genome sequencing was performed prospectively on travellers arriving from Brazil and on a random selection of SARS-CoV-2 positive cases from our population.RESULTS:
In this study we report the first SARS-CoV-2 P.1 and P.2 variants exported from Brazil to Spain. The case infected with the P.1 variant, who had only stayed in Rio de Janeiro, required hospitalisation. The two P.2 cases remained asymptomatic. A wider distribution for P.1 variant beyond the Brazilian Amazonia should be considered. The exportation of the P.2 variant, carrying the E484K mutation, deserves attention. One month after the first description of P.1 and P.2 importations from Brazil to Madrid, these variants were identified circulating in the community, in cases without a travel history, and involved in household transmissionsCONCLUSION:
Whole genome sequencing of SARS-CoV-2 positive travellers arriving from Brazil allowed us to identify the first importations of P.1 and P.2 variants to Spain and their early community transmission.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
SARS-CoV-2
/
COVID-19
Type of study:
Observational study
/
Prognostic study
/
Randomized controlled trials
Topics:
Variants
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
/
Europa
Language:
English
Journal:
Enferm Infecc Microbiol Clin (Engl Ed)
Year:
2022
Document Type:
Article
Affiliation country:
J.eimce.2021.05.015
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