Association Between ABO Blood Group System and COVID-19 Severity.
Am J Clin Pathol
; 158(5): 570-573, 2022 11 03.
Article
in English
| MEDLINE | ID: covidwho-20233576
ABSTRACT
OBJECTIVES:
A possible association between blood group systems (ABO and Rh) and coronavirus disease 2019 (COVID-19) severity has recently been investigated by various studies with conflicting results. However, due to variations in the prevalence of the ABO and Rh blood groups in different populations, their association with COVID-19 might be varied as well. Therefore, we conducted this study on Libyan participants to further investigate this association and make population-based data available to the worldwide scientific community.METHODS:
In this case-control study, ABO and Rh blood groups in 419 confirmed COVID-19 cases in Zawia, Libya, and 271 healthy controls were compared using descriptive statistics and χâ2 tests.RESULTS:
Blood group A was significantly more prevalent in patients with severe COVID-19 (64/125; 51.2%) than in patients with nonsevere COVID-19 (108/294, 36.7%) (Pâ <â .034), whereas the O blood group prevalence was higher in nonsevere COVID-19 cases (131/294, 44.5%) compared with severe cases (43/125, 34.4%) (Pâ <â .001).CONCLUSIONS:
The results showed a significant association between blood group A and the severity of COVID-19, whereas patients with blood group O showed a low risk of developing severe COVID-19 infection. No significant association was found between Rh and susceptibility/severity of the disease.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
ABO Blood-Group System
/
COVID-19
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Humans
Language:
English
Journal:
Am J Clin Pathol
Year:
2022
Document Type:
Article
Affiliation country:
Ajcp
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