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Differences in Post-mRNA Vaccination Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Immunoglobulin G (IgG) Concentrations and Surrogate Virus Neutralization Test Response by Human Immunodeficiency Virus (HIV) Status and Type of Vaccine: A Matched Case-Control Observational Study.
Spinelli, Matthew A; Peluso, Michael J; Lynch, Kara L; Yun, Cassandra; Glidden, David V; Henrich, Timothy J; Deeks, Steven G; Gandhi, Monica.
  • Spinelli MA; Division of HIV, ID, and Global Medicine, University of California, San Francisco, San Francisco, California, USA.
  • Peluso MJ; Division of HIV, ID, and Global Medicine, University of California, San Francisco, San Francisco, California, USA.
  • Lynch KL; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, USA.
  • Yun C; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, USA.
  • Glidden DV; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA.
  • Henrich TJ; Division of HIV, ID, and Global Medicine, University of California, San Francisco, San Francisco, California, USA.
  • Deeks SG; Division of HIV, ID, and Global Medicine, University of California, San Francisco, San Francisco, California, USA.
  • Gandhi M; Division of HIV, ID, and Global Medicine, University of California, San Francisco, San Francisco, California, USA.
Clin Infect Dis ; 75(1): e916-e919, 2022 Aug 24.
Article in English | MEDLINE | ID: covidwho-2017794
ABSTRACT
Following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccination, people living with human immunodeficiency virus (HIV, PLWH) had lower surrogate virus neutralization test response (P = .03) and a trend toward lower immunoglobulin G (IgG) response (P = .08), particularly among those with lower CD4+ T-cell counts and who received the BNT162b2 vaccine. Study of the impact of supplemental vaccine doses among PLWH is needed.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Viral Vaccines / COVID-19 Type of study: Observational study / Prognostic study Topics: Long Covid / Vaccines Limits: Humans Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: Cid

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Viral Vaccines / COVID-19 Type of study: Observational study / Prognostic study Topics: Long Covid / Vaccines Limits: Humans Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: Cid