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Persistent circulating SARS-CoV-2 spike is associated with post-acute COVID-19 sequelae.
Swank, Zoe; Senussi, Yasmeen; Manickas-Hill, Zachary; Yu, Xu G; Li, Jonathan Z; Alter, Galit; Walt, David R.
  • Swank Z; Harvard Medical School, Boston, MA, USA.
  • Senussi Y; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.
  • Manickas-Hill Z; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.
  • Yu XG; Harvard Medical School, Boston, MA, USA.
  • Li JZ; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.
  • Alter G; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.
  • Walt DR; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Clin Infect Dis ; 2022 Sep 02.
Article in English | MEDLINE | ID: covidwho-2236036
ABSTRACT
The diagnosis of post-acute sequelae of COVID-19 (PASC) poses an ongoing medical challenge. To identify biomarkers associated with PASC we analyzed plasma samples collected from PASC and COVID-19 patients to quantify viral antigens and inflammatory markers. We detect SARS-CoV-2 spike predominantly in PASC patients up to 12 months post-diagnosis.
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Full text: Available Collection: International databases Database: MEDLINE Topics: Long Covid Language: English Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: Cid

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Full text: Available Collection: International databases Database: MEDLINE Topics: Long Covid Language: English Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: Cid