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Nucleocapsid Antigenemia in Patients Receiving Anti-CD20 Therapy With Protracted COVID-19.
Wilber, Eli; Piantadosi, Anne; Babiker, Ahmed; McLendon, Kaleb; O'Sick, William; Fitts, Eric; Webster, Andrew S; Verkerke, Hans; Kim, James S; Phadke, Varun K; Rouphael, Nadine; Titanji, Boghuma K; Blake, William T; Howard-Anderson, Jessica; Roback, John D; Lam, Wilbur A; Damhorst, Gregory L.
  • Wilber E; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Piantadosi A; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Babiker A; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • McLendon K; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • O'Sick W; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Fitts E; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Webster AS; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Verkerke H; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Kim JS; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Phadke VK; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Rouphael N; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Titanji BK; Division of Hospital Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Blake WT; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Howard-Anderson J; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Roback JD; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Lam WA; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Damhorst GL; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Open Forum Infect Dis ; 9(8): ofac419, 2022 Aug.
Article in English | MEDLINE | ID: covidwho-2018041
ABSTRACT
Immunocompromised patients with prolonged coronavirus disease 2019 symptoms present diagnostic and therapeutic challenges. We measured viral nucleocapsid antigenemia in 3 patients treated with anti-CD20 immunotherapy who acquired severe acute respiratory syndrome coronavirus 2 infection and experienced protracted symptoms. Our results support nucleocapsid antigenemia as a marker of persistent infection and therapeutic response.
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Full text: Available Collection: International databases Database: MEDLINE Topics: Long Covid Language: English Journal: Open Forum Infect Dis Year: 2022 Document Type: Article Affiliation country: Ofid

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Full text: Available Collection: International databases Database: MEDLINE Topics: Long Covid Language: English Journal: Open Forum Infect Dis Year: 2022 Document Type: Article Affiliation country: Ofid