A retrospective review of paediatric neurosurgical suppurative intracranial infections

ABSTRACT

836 Figure 1 Origin by age[Figure omitted. See PDF] 836 Table 1Patient Culture and AbxConclusionSuppurative intracranial infections are rare but serious neurological diseases. This cohort demonstrated a decrease in the incidence of Paediatric Suppurative Brain Infection in 2020-2021 of 78% (p<0.003). This correlated with the first year of the SARS-CoV-2 pandemic.This audit supports a high clinical suspicion for brain abscess in children with a recent infection, particularly sinusitis. Ceftriaxone and Metronidazole are an adequate first line empiric treatment, with adjustment according to sensitivities.The emerging patterns in this audit are supported by similar, larger studies;this data presents valuable information for the management of paediatric intracranial infections and informs further studies.ReferencesPaediatric focal intracranial suppurative infection a UK single-centre retrospective cohort study, Van der Velden et al.Clinical and Microbiologic Features Guiding Treatment Recommendations for Brain Abscesses in Children, Felsenstein et al.