Reactivation of adult-onset Still's disease after use of the COVID-19 ChAdOx1-S vaccine.
BMJ Case Rep
; 15(8)2022 Aug 26.
Article
in English
| MEDLINE | ID: covidwho-2019947
ABSTRACT
A woman in her 60s with a history of adult-onset Still's disease (AOSD) in remission for 14 years received the ChAdOx1-S vaccine as a booster to her initial vaccination schedule (two doses of CoronaVac vaccine 6 months apart). Two weeks later, she consulted for symptoms suggestive of AOSD reactivation. This was confirmed during hospitalisation, where renal and cardiac involvement were also observed. Despite using high-dose corticosteroids, troponin T and N-terminal pro hormone B-type natriuretic peptide (NT-proBNP) were persistently elevated. Tocilizumab was used, with which the patient achieved complete remission of her symptoms and normalised her laboratory tests.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Still's Disease, Adult-Onset
/
COVID-19
/
ChAdOx1 nCoV-19
Type of study:
Case report
/
Prognostic study
Topics:
Long Covid
/
Vaccines
Limits:
Female
/
Humans
/
Middle aged
Language:
English
Year:
2022
Document Type:
Article
Affiliation country:
Bcr-2022-249290
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