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An Autopsy Report of a Case with Cerebral Infarction Complicated by Coronavirus Disease 2019 Infection.
Goto, Ryoji; Kawakami, Haruka; Horiuchi, Yurino; Chikada, Ayaka; Yasuda, Tsutomu; Suzuki, Tetsuya; Miyazato, Yusuke; Ishikane, Masahiro; Kishino, Yuya; Miyazaki, Hideki; Igari, Toru; Katano, Harutaka; Suzuki, Tadaki; Murayama, Shigeo; Arai, Noritoshi.
  • Goto R; Department of Neurology, National Center for Global Health and Medicine, Japan.
  • Kawakami H; Department of Neurology, Tokyo Metropolitan Geriatric Hospital, Japan.
  • Horiuchi Y; Department of Neurology, National Center for Global Health and Medicine, Japan.
  • Chikada A; Department of Neurology, National Center for Global Health and Medicine, Japan.
  • Yasuda T; Department of Neurology, National Center for Global Health and Medicine, Japan.
  • Suzuki T; Department of Neurology, National Center for Global Health and Medicine, Japan.
  • Miyazato Y; Disease Control and Prevention Center, National Center for Global Health and Medicine, Japan.
  • Ishikane M; Disease Control and Prevention Center, National Center for Global Health and Medicine, Japan.
  • Kishino Y; Disease Control and Prevention Center, National Center for Global Health and Medicine, Japan.
  • Miyazaki H; Department of Pathology, National Center for Global Health and Medicine, Japan.
  • Igari T; Department of Pathology, Graduate School of Medicine, the University of Tokyo, Japan.
  • Katano H; Department of Pathology, National Center for Global Health and Medicine, Japan.
  • Suzuki T; Department of Pathology, National Center for Global Health and Medicine, Japan.
  • Murayama S; Department of Pathology, National Institute of Infectious Diseases, Japan.
  • Arai N; Department of Pathology, National Institute of Infectious Diseases, Japan.
Intern Med ; 61(22): 3439-3444, 2022 Nov 15.
Article in English | MEDLINE | ID: covidwho-2022248
ABSTRACT
We herein report a case of cerebral infarct in a patient with coronavirus disease 2019 (COVID-19) infection who died of aspiration pneumonia. The postmortem examination of the brain revealed embolic infarct with negative findings on quantitative reverse transcription polymerase chain reaction (qRT-PCR) as well as immunohistochemistry to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The systemic examination only revealed low copy numbers of SARS-CoV-2 in the bronchus. This is the first and so far only autopsy case of COVID-19 infection with pathologic and virologic findings of the postmortem brain in Japan.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Case report / Diagnostic study Topics: Long Covid Limits: Humans Language: English Journal: Intern Med Journal subject: Internal Medicine Year: 2022 Document Type: Article Affiliation country: Internalmedicine.9726-22

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Case report / Diagnostic study Topics: Long Covid Limits: Humans Language: English Journal: Intern Med Journal subject: Internal Medicine Year: 2022 Document Type: Article Affiliation country: Internalmedicine.9726-22