Your browser doesn't support javascript.
Risk factors associated with indoor transmission during home quarantine of COVID-19 patients.
Liu, Yang; Chai, Yan-Hua; Wu, Yi-Fan; Zhang, Yu-Wei; Wang, Ling; Yang, Ling; Shi, Yi-Han; Wang, Le-Le; Zhang, Li-Sha; Chen, Yan; Fan, Rui; Wen, Yu-Hua; Yang, Heng; Li, Li; Liu, Yi-Han; Zheng, Hui-Zhen; Jiang, Ji-Jin; Qian, Hao; Tao, Ru-Jia; Qian, Ye-Chang; Wang, Ling-Wei; Chen, Rong-Chang; Xu, Jin-Fu; Wang, Chen.
  • Liu Y; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Chai YH; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Wu YF; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Zhang YW; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Wang L; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Yang L; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Shi YH; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Wang LL; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Zhang LS; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Chen Y; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Fan R; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Wen YH; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Yang H; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Li L; Department of Respiratory Medicine, Baoshan District Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai, China.
  • Liu YH; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Zheng HZ; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Jiang JJ; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Qian H; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Tao RJ; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Qian YC; Department of Respiratory Medicine, Baoshan District Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai, China.
  • Wang LW; Shenzhen Institute of Respiratory Disease, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, China.
  • Chen RC; Shenzhen Clinical Research Centre for Respirology, Shenzhen People's Hospital, Shenzhen, China.
  • Xu JF; Shenzhen Institute of Respiratory Disease, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, China.
  • Wang C; Shenzhen Clinical Research Centre for Respirology, Shenzhen People's Hospital, Shenzhen, China.
Front Public Health ; 11: 1170085, 2023.
Article in English | MEDLINE | ID: covidwho-20231258
ABSTRACT

Purpose:

The study aimed to identify potential risk factors for family transmission and to provide precautionary guidelines for the general public during novel Coronavirus disease 2019 (COVID-19) waves.

Methods:

A retrospective cohort study with numerous COVID-19 patients recruited was conducted in Shanghai. Epidemiological data including transmission details, demographics, vaccination status, symptoms, comorbidities, antigen test, living environment, residential ventilation, disinfection and medical treatment of each participant were collected and risk factors for family transmission were determined.

Results:

A total of 2,334 COVID-19 patients participated. Compared with non-cohabitation infected patients, cohabitated ones were younger (p = 0.019), more commonly unvaccinated (p = 0.048) or exposed to infections (p < 0.001), and had higher rates of symptoms (p = 0.003) or shared living room (p < 0.001). Risk factors analysis showed that the 2019-nCov antigen positive (OR = 1.86, 95%CI 1.40-2.48, p < 0.001), symptoms development (OR = 1.86, 95%CI 1.34-2.58, p < 0.001), direct contact exposure (OR = 1.47, 95%CI 1.09-1.96, p = 0.010) were independent risk factors for the cohabitant transmission of COVID-19, and a separate room with a separate toilet could reduce the risk of family transmission (OR = 0.62, 95%CI 0.41-0.92, p = 0.018).

Conclusion:

Patients showing negative 2019-nCov antigen tests, being asymptomatic, living in a separate room with a separate toilet, or actively avoiding direct contact with cohabitants were at low risk of family transmission, and the study recommended that avoiding direct contact and residential disinfection could reduce the risk of all cohabitants within the same house being infected with COVID-19.
Subject(s)
Keywords
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Observational study / Prognostic study Topics: Vaccines Limits: Humans Country/Region as subject: Asia Language: English Journal: Front Public Health Year: 2023 Document Type: Article Affiliation country: Fpubh.2023.1170085

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Observational study / Prognostic study Topics: Vaccines Limits: Humans Country/Region as subject: Asia Language: English Journal: Front Public Health Year: 2023 Document Type: Article Affiliation country: Fpubh.2023.1170085