Estimate of immunoglobulin G, M, and some liver enzymes levels in Covid-19 patients and relation with blood group in Najaf governorate, Iraq

ABSTRACT

The COVID19 disease is a transmittable viral infection that causes acute respiratory system infection, to this day there is no proven treatment for this virus and its complication in the body are still unclear. so the current study aimed to determine the levels of immunoglobulin (M, G) against infection with covid 19, the measure of liver enzymes(AST, ALT), and the relation of infection with blood group. This study included 60 patients infected by COVID-19 and 30 uninfected people, who came to the AL-Najaf Hospitals from January to March month 2020. Draw 5 ml of blood for the measure of G, M, and AST, ALT levels, and determine the blood group. The results showed that infection with the Covid-19 virus had a significant effect (p <0.001) on the level of both G and M antibodies compared to the control group (10.18, 16.94) mg/dl, (0.320,0.312) mg/dl, respectively. also, the study showed the significant effect of infection on liver enzymes which caused increased AST and ALT levels (44.25,52.30)U/L compared with the control group (36.28, 42.46) U/L respectively.also explained the relation between blood group and covid 19 infection, as a blood group A recorded the highest rate of infection and blood type O lowest rate of infection (35, 13.33) % respectively. so it is possible to rely on measuring the level of G, M antibodies in diagnosing or recovering from covid 19 infection.also, know the effect of the infection on the liver and the relationship between infection and blood group. © 2023 Author(s).