Retrospective nested study of demographic characteristics, lethality and discharge rate of COVID-19 inpatients in central south of Bulgaria
Bulgarian Journal of Public Health
; 15(1):38-44, 2023.
Article
in English, Bulgarian
| GIM | ID: covidwho-20235122
ABSTRACT
Introduction:
SARS-CoV-2 infection has affected more than 683 million people worldwide with 6.8 million deaths. Unfortunately, Bulgaria is one of the most severely affected European Union (EU) member-states with one of the highest mortality rates.Aim:
The study aims to provide a description of the demographic characteristics, discharge rate, and fatality rate of COVID-19-diagnosed patients in one region of Central South Bulgaria in 2021. Materials andmethods:
A retrospective nested case series study was conducted among patients hospitalized with a confirmed diagnosis of SARS-CoV-2 infection between January 1st and December 31st, 2021. Anonymized patient data on age, sex, admission and discharge dates, treatment, and the outcome was collected from hospital electronic patient records and analyzed using descriptive statistics.Results:
Data from 1630 (51% male) patients were identified. The mean age was 63.64 years (+or-15.23). 1342 (82%) of the patients were discharged. The mean age of the diseased was 70.88 years (+or-10.05). 1455 (89%) patients received only symptomatic therapy, 155 (10%) patients were treated with remdesivir (VekluryR), 11 (1%) patients were treated with casirivimab/imdevimab (RonapreveR) and 9 (1%) patients were administered regdanvimab (RegkironaR).Conclusions:
The study results demonstrate that Bulgarian patients with COVID-19 were treated according to the best global and national evidencebased guidelines. Lethality and discharge rates are in concordance with global trends and outcomes.
1809249-37-3; retrospective studies; mortality; human diseases; patients; clinical aspects; disease course; viral diseases; coronavirus disease 2019; monoclonal antibodies; remdesivir; drug therapy; medical treatment; antiviral agents; man; Severe acute respiratory syndrome coronavirus 2; Bulgaria; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; eukaryotes; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; Balkans; Southern Europe; Europe; European Union Countries; upper-middle income countries; very high Human Development Index countries; casirivimab; imdevimab; regdanvimab; death rate; SARS-CoV-2; clinical picture; disease progression; viral infections; chemotherapy; antivirals
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Collection:
Databases of international organizations
Database:
GIM
Type of study:
Observational study
/
Prognostic study
Language:
Bulgarian
/
English
Journal:
Bulgarian Journal of Public Health
Year:
2023
Document Type:
Article
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