Factors Associated with SARS-CoV-2 Infection before Vaccination among European Health Care Workers.
Med Lav
; 114(3): e2023022, 2023 Jun 12.
Article
in English
| MEDLINE | ID: covidwho-20239228
ABSTRACT
BACKGROUND:
Health care workers (HCWs) were on the frontline of the current pandemic. We aimed at identifying determinants of SARS-CoV-2 infection and the effectiveness of personal protection equipment (PPE) worn by HCWs before vaccination.METHODS:
We abstracted data on SARS-CoV-2 infection based on positive PCR results and sociodemographic characteristics of 38,793 HCWs from public hospitals and public health authorities from 10 European centers. We fitted cohort-specific multivariate logistic regression models to identify determinants of infection and combined the results using random-effects meta-analyses.RESULTS:
The overall prevalence of infection before vaccination among HCWs was 9.58%. Infection was associated with the presence of selected symptoms; no association was found between sociodemographic factors and increased risk of infection. The use of PPE and particularly FFP2/FFP3 masks had a different protective effect during the first and second waves of the COVID pandemic.CONCLUSIONS:
The study provides evidence that mask use was the most effective PPE in preventing SARS-CoV-2 infection among HCWs.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Cohort study
/
Observational study
/
Prognostic study
/
Randomized controlled trials
/
Reviews
Topics:
Vaccines
Limits:
Humans
Language:
English
Journal:
Med Lav
Year:
2023
Document Type:
Article
Affiliation country:
Mdl.v114i3.14422
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