Progress and treatment of "long COVID" in non-hospitalized patients: A single-center retrospective cohort study
Traditional and Kampo Medicine
; 2023.
Article
in English
| EMBASE | ID: covidwho-20240820
ABSTRACT
Background:
"Long COVID" or "post-COVID conditions" describes prolonged symptoms after the acute phase of coronavirus disease 2019 (COVID-19). However, there is a paucity of published reports on its treatment. Method(s) This retrospective cohort study included adult, non-hospitalized patients with COVID-19 symptoms at least one month after the onset who had been examined at the isolation facility in Miyagi prefecture between October 2020 and September 2021. Result(s) In total, 70 patients with a median age of 46 (21-69) years were included, and 37 were women (52.9%). The median time from onset to the end of treatment was 46 (28-396) days. Thirty-eight patients (53.5%) showed improvement in all symptoms, while four (5.7%) did not recover within the study period. The symptoms at six months with high residual rates were dizziness (33.3%), fatigue (14.3%), myalgia (14.3%), abdominal discomfort (14.3%), and taste dysfunction (11.8%). For treatment of prolonged symptoms, formulae of Kampo medicine (Japanese traditional medicine) were used alone or in combination with Western medications in 76%, 66%, 53%, and 66% of patients at 1-2 months, 2-3 months, 3-6 months, and over 6 months respectively. Kampo formulae with anti-inflammatory effects were used in the early period;however, tonifying formulae and blood stasis-resolving formulae were used in the late period. Conclusion(s) Non-hospitalized patients with COVID-19 may suffer from persistent symptoms after the acute phase of infection. For the management of long COVID, a comprehensive and holistic approach is needed. Kampo medicine should be considered as a treatment option for long COVID.Copyright © 2023 The Authors. Traditional & Kampo Medicine published by John Wiley & Sons Australia, Ltd on behalf of Japan Society for Oriental Medicine and Japan Society of Medical and Pharmaceutical Sciences for Traditional Medicine.
cohort study; Kampo; long COVID; non-hospitalized; post-COVID condition; traditional medicine; abdominal discomfort; adult; antiinflammatory activity; article; cohort analysis; coronavirus disease 2019; dizziness; fatigue; female; hemostasis; human; isolation facility; Kampo medicine; major clinical study; middle aged; myalgia; retrospective study; Kampo medicine (drug)
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Cohort study
/
Observational study
/
Prognostic study
Topics:
Long Covid
/
Traditional medicine
Language:
English
Journal:
Traditional and Kampo Medicine
Year:
2023
Document Type:
Article
Similar
MEDLINE
...
LILACS
LIS