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Nanosponges: As a Dynamic Drug Delivery Approach for Targeted Delivery
International Journal of Applied Pharmaceutics ; 15(3):1-11, 2023.
Article in English | EMBASE | ID: covidwho-20242785
ABSTRACT
Recent advancements in nanotechnology have resulted in improved medicine delivery to the target site. Nanosponges are three-dimensional drug delivery systems that are nanoscale in size and created by cross-linking polymers. The introduction of Nanosponges has been a significant step toward overcoming issues such as drug toxicity, low bioavailability, and predictable medication release. Using a new way of nanotechnology, nanosponges, which are porous with small sponges (below one microm) flowing throughout the body, have demonstrated excellent results in delivering drugs. As a result, they reach the target place, attach to the skin's surface, and slowly release the medicine. Nanosponges can be used to encapsulate a wide range of medicines, including both hydrophilic and lipophilic pharmaceuticals. The medication delivery method using nanosponges is one of the most promising fields in pharmacy. It can be used as a biocatalyst carrier for vaccines, antibodies, enzymes, and proteins to be released. The existing study enlightens on the preparation method, evaluation, and prospective application in a medication delivery system and also focuses on patents filed in the field of nanosponges.Copyright © 2023 The Authors.
Keywords
Controlled release; Cross-linkers; Nanosponges; Topical application; beta-cyclo-dextrin and polymers; analytic method; antiviral activity; bioavailability; biocatalyst; biocompatibility; bioremediation; cancer therapy; cross linking; crystallization; diffusion; dispersity; drug delivery system; drug efficacy; drug formulation; drug release; drug stability; drug synthesis; electrospinning; encapsulation; Fourier transform infrared spectroscopy; hydrophilicity; infrared spectrophotometry; lipophilicity; melting point; microscopy; microwave radiation; molecularly targeted therapy; mycosis; nanoemulsion; particle size; photon correlation spectroscopy; prospective study; Raman spectrometry; review; Severe acute respiratory syndrome coronavirus 2; size exclusion chromatography; skin surface; thermal analysis; thin layer chromatography; topical drug administration; toxicological parameters; viscosity; X ray powder diffraction; zeta potential; antibody; cosmetic; nanoparticle/an [Drug Analysis]; nanoparticle/dv [Drug Development]; nanoparticle/to [Drug Toxicity]; nanoparticle/pr [Pharmaceutics]; polymer; unclassified drug; vaccine; sensor; bubble electrospinning; cyclodextrin based nanosponges; drug loading efficiency; emulsion-solvent diffusion method; melt method; quasi emulsion solvent method; solvent method; ultrasound assisted synthesis; hyper linked polystyrene based nanosponges; nanosponges/an [Drug Analysis]; nanosponges/dv [Drug Development]; nanosponges/to [Drug Toxicity]; nanosponges/pr [Pharmaceutics]; silicon based nanosponges; titanium based nanosponges; chemical sensor

Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Language: English Journal: International Journal of Applied Pharmaceutics Year: 2023 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Language: English Journal: International Journal of Applied Pharmaceutics Year: 2023 Document Type: Article