The Role of the Immune System on the Cardiac Complications Observed in SARS-CoV-2
Int. j. cardiovasc. sci. (Impr.)
; 35(3): 410-418, May-June 2022. graf
Article
in English
| WHO COVID, LILACS (Americas) | ID: covidwho-20244272
Responsible library:
BR1.1
ABSTRACT
Abstract An acute respiratory syndrome caused by SARS-CoV2 was declared a pandemic by the World Health Organization. Current data in the world and in Brazil show that approximately 40% of patients who died have some type of cardiac comorbidity. There are also robust reports showing an increase in IL-6 / IL-1B / TNF-alpha and the presence of lymphopenia in patients with COVID-19. Our team and others have shown that increased cytokines are the link between arrhythmias/Left ventricular dysfunction and the immune system in different diseases. In addition, it has been well demonstrated that lymphopenia can not only be a good marker, but also a factor that causes heart failure. Thus, the present review focused on the role of the immune system upon the cardiac alterations observed in the SARS-CoV2 infection. Additionally, it was well described that SARS-CoV-2 is able to infect cardiac cells. Therefore, here it will be reviewed in deep.
Keywords
Full text:
Available
Collection:
International databases
Database:
WHO COVID
/
LILACS (Americas)
Main subject:
Arrhythmias, Cardiac
/
SARS-CoV-2
/
COVID-19
/
Heart Failure
/
Myocardium
Topics:
Long Covid
Language:
English
Journal:
Int. j. cardiovasc. sci. (Impr.)
Journal subject:
Cardiology
Year:
2022
Document Type:
Article
Institution/Affiliation country:
Federal University of Rio de Janeiro/BR
/
Universidade Federal do Rio de Janeiro/BR
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